Related Experiment Video
Updated: Aug 30, 2025
08:05
Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
14.3K
Diffused bladder wall calcification in a survivor with severe coronavirus disease 2019: A case report
Pai-Yu Cheng1,2, Yi-You Huang1, Fu-Shan Jaw1
1Department of Biomedical Engineering, College of Medicine and College of Engineering, National Taiwan University, Taiwan.
Medicine
|August 31, 2022
Summary
Severe COVID-19 can lead to bladder calcification, a rare condition causing urinary symptoms. This case highlights a potential long-term complication of the infection, emphasizing the need for further investigation in affected patients.
Area of Science:
- Urology
- Infectious Diseases
- Nephrology
Background:
- Bladder calcification is uncommon, with prior associations to infections, schistosomiasis, tuberculosis, cancer, and inflammatory conditions.
- Severe COVID-19 is characterized by a cytokine storm and systemic inflammation, with reported long-term complications including coronary artery and lung calcification.
Observation:
- A 68-year-old male presented with persistent lower urinary tract symptoms post-severe COVID-19.
- Urine cultures were negative for urea-splitting bacteria.
- Cystoscopy revealed diffuse calcification of the bladder mucosa and submucosa.
Findings:
- Transurethral lithotripsy successfully removed the mucosal calcification.
- Stone analysis revealed a composition of 98% calcium phosphate and 2% calcium oxalate.
- The patient's lower urinary tract symptoms resolved, with no recurrence of calcification on follow-up.
Implications:
- Diffuse bladder calcification may represent a sequela of COVID-19 infection.
- New-onset lower urinary tract symptoms following severe COVID-19 warrant thorough investigation for potential urinary tract complications.
- This finding expands the spectrum of known long-term complications associated with severe coronavirus disease 2019.
Related Concept Videos
01:26Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
35
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
35
01:30Urinary Tract Calculi III: Medical Management
19
The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
19
01:28Urinary Tract Calculi I: Introduction
35
Renal calculi, or kidney stones, are solid deposits of minerals and salts formed inside the kidneys. In medical terminology, "calculus" refers to the stone itself, while "lithiasis" describes the process of stone formation. Depending on their location within the urinary system, these stones may be classified as either urolithiasis, when situated within the urinary tract, or nephrolithiasis, when located within the kidneys. Each term signifies the specific impact of the stone.Predisposition...
35
01:28Urinary Tract Calculi V: Nursing Management
24
AssessmentSubjective Data: Obtain a detailed health history, including any recent or chronic urinary tract infections, periods of immobilization, previous episodes of renal calculi, and medical conditions such as gout, benign prostatic hyperplasia, or hyperparathyroidism. Review the medication history for drugs that may influence stone formation, including allopurinol, analgesics, loop diuretics, or thiazide diuretics. Document the use of long-term indwelling catheters and any past surgical...
24
01:25Urinary Tract Calculi VI: Surgical Management
22
Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
22
01:23Urinary Bladder
1.3K
The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
1.3K