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Updated: Aug 30, 2025

Modified Single-Loop Reconstruction for Pancreaticoduodenectomy
Published on: September 28, 2019
Individualized pharmaceutical care for a patient after pancreaticoduodenectomy with trypsin replacement nutritional
Song Zhang1, Qin Tan2, Hanjun He1
1The First People's Hospital of Guangyuan, Guangyuan, China.
Rationale:
Optimal nutritional therapy for pancreaticoduodenectomy (PD) has been debated; however, little is known about key points of pancreatin enteric-coated capsule administration, a critical component of the PD treatment regimen. Patients often report elevations in tablet platoon and steatorrhea, and steatorrhea may adversely affect nutritional therapy for PD. Herein, we report a case of individualized pharmaceutical care for a patient after PD with trypsin replacement nutritional therapy.
Patient Concerns And Diagnosis:
After PD with trypsin replacement nutritional therapy, the patient developed acute steatorrhea.
Intervention:
Individualized pharmaceutical care was provided by clinical pharmacists to address intolerance to pancreatin enteric-coated capsules following PD.
Outcomes:
The clinical pharmacist's integration into the patient's treatment plan enhanced pharmacotherapy optimization, especially through pharmacokinetic monitoring and interventions related to nutritional therapy.
Lesson:
Pharmaceutical care by clinical pharmacists aids in ensuring the safety and efficacy of drugs and nutritional treatment. Clinical pharmacists should be members of the nutrition support team.
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