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A novel IgG Fc by computer-aided design enhances heavy-chain heterodimerization in bi- or trispecific antibodies

Bo Wang1, Jun Lin2,3, Matthew R Hoag1

  • 1Ab Studio, Inc., Hayward, CA 94545, USA.

Antibody Therapeutics
|August 31, 2022
PubMed

Keywords:
Fc engineeringbispecific antibodiescomputer-aided antibody designheavy chain heterodimerizationknob-into-holemulti-specific antibodiestrispecific antibodies

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