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Extensive small intestinal diffuse large B cell lymphoma.
Xiaoran Liu1, Tongyu Lv1, Xueyan Zhang1
1Nursing, Binzhou Medical University.
Revista Espanola De Enfermedades Digestivas
|August 31, 2022
Summary
A patient with diffuse large B-cell lymphoma experienced intestinal perforation and underwent surgery, chemotherapy, and stem cell transplant. Follow-up imaging showed significant improvement, indicating successful treatment for this aggressive cancer.
Area of Science:
- Oncology
- Gastroenterology
- Hematology
Background:
- Diffuse large B-cell lymphoma (DLBCL) is an aggressive non-Hodgkin lymphoma.
- Intestinal complications, such as perforation, can occur in DLBCL patients.
Observation:
- A 32-year-old male presented with abdominal pain and small intestinal perforation secondary to DLBCL.
- Imaging revealed diffuse small intestinal wall thickening, lumen stenosis, and mesenteric lymphadenopathy.
- The patient experienced bladder compression due to abdominal distension.
Findings:
- The patient received rituximab chemotherapy and autologous stem cell transplantation.
- Post-treatment CT scans demonstrated marked improvement in intestinal wall thickening and resolution of lymphadenopathy.
- Clinical follow-up at 6 months indicated the patient was in good health.
Implications:
- This case highlights the successful management of a rare intestinal complication of DLBCL.
- Combined modality treatment, including chemotherapy and stem cell transplantation, can lead to significant recovery.
- Early diagnosis and aggressive therapy are crucial for improving outcomes in DLBCL patients with gastrointestinal involvement.
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