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Updated: Aug 30, 2025
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Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
Published on: February 13, 2021
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The evolving face of heart failure management
Mandeep Singh Kalsi1, Nalin Dayawansa2, Josh Winderlich3
1MBBS, AMC, Cert EM (ACEM), Cardiology Registrar, Department of Cardiology, The Northern Hospital, Northern Health, Epping, Vic.
Australian Journal of General Practice
|September 1, 2022
Summary
New heart failure (HF) medications, including angiotensin-neprilysin inhibitors (ARNIs) and sodium-glucose co-transporter-2 (SGLT2) inhibitors, offer survival benefits but are underused. Increased GP familiarity can improve patient outcomes in HF management.
Area of Science:
- Cardiology
- Pharmacology
Background:
- Heart failure (HF) is a significant cause of illness and death in Australia.
- Current HF therapeutic options are limited, but new drug classes are emerging.
Purpose of the Study:
- To update general practitioners (GPs) on HF management.
- To increase GP familiarity with ARNIs and SGLT2 inhibitors for improved HF treatment.
Main Methods:
- Review of stepwise diagnosis, treatment, and monitoring in HF.
- Focus on the role of ARNIs and SGLT2 inhibitors in HF care.
Main Results:
- ARNIs and SGLT2 inhibitors reduce morbidity and improve survival in HF with reduced ejection fraction.
- These novel medications remain underutilized in clinical practice.
Conclusions:
- Increased GP knowledge of ARNIs and SGLT2 inhibitors can enhance their uptake.
- Maximizing the use of these drugs will benefit patients with HF.
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