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Post-COVID Mucormycosis of Mandible: A Conundrum of Management

Ashish Gopal1, Raman Sharma1, Sakshi Negi1

  • 1Otolaryngology - Head and Neck Surgery, Maulana Azad Medical College, New Delhi, IND.

Cureus
|September 1, 2022
PubMed

Insights

Post-COVID-19 mucormycosis can affect the mandible, a rare occurrence. This case highlights conservative management as a viable alternative to surgery for isolated mandibular mucormycosis.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Oral and Maxillofacial Surgery

Background:

  • Mucormycosis is an aggressive fungal infection, often affecting immunocompromised individuals, with a noted increase post-COVID-19.
  • Risk factors include diabetes mellitus, hematological malignancies, and prolonged steroid use, contributing to invasive fungal infections.
  • The spread typically involves paranasal sinuses, orbital, and cranial structures, with isolated mandibular involvement being exceptionally rare.

Observation:

  • This report details a unique case of isolated mandibular mucormycosis following COVID-19 infection.
  • The patient presented with a rare manifestation of mucormycosis affecting only the mandible.
  • Standard treatment involves surgical resection and reconstruction, followed by antifungal therapy.

Findings:

  • The study presents a case of isolated mandibular mucormycosis in a post-COVID-19 patient.
  • Conservative management was chosen over surgical intervention due to potential complications and patient morbidity.
  • This approach offers an alternative strategy for managing rare cases of mandibular mucormycosis.

Implications:

  • This case suggests conservative management may be effective for isolated mandibular mucormycosis, reducing patient morbidity.
  • It expands the understanding of mucormycosis presentation and treatment options, particularly in the context of post-COVID-19 complications.
  • Further research is warranted to evaluate the efficacy and long-term outcomes of conservative management for this rare condition.
Keywords:
covid 19fungalmandiblemandibulectomymucormycosis

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