Related Experiment Video
Updated: Aug 30, 2025

Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer
Published on: July 28, 2010
Can a Banana a Day Keep the Cancer Away in Patients with Lynch Syndrome?
Ajay Bansal1,2, Robert Montgomery3, Eduardo Vilar4
1Division of Gastroenterology and Hepatology, The University of Kansas Medical Center, Kansas City, Kansas.
Abstract:
The CAPP2 investigators report on the long-term effects of resistant starch (RS) on the incidence of colorectal cancer and other Lynch syndrome-related tumors in the trial population of the CAPP-2 study. RS has no effect on colorectal cancer incidence, but it reduced the numbers of other Lynch syndrome-related tumors, mainly driven by upper gastrointestinal cancers. Although the study has limitations related to secondary analysis, it fills an important void in the field of cancer interception of non-colorectal Lynch syndrome-related tumors and should form the basis for future trials of RS in Lynch syndrome. See related article, p. 623.
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