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Related Experiment Video

Updated: Aug 30, 2025

Author Spotlight: Advancing Pelvic Prolapse Treatment with a Non-Mesh Approach using Laparoscopic Pectopexy
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Cognitive function following surgery for pelvic organ prolapse.

Daisy Hassani1, Nathanael Koelper2, Yelizaveta Borodyanskaya1

  • 1Department of Obstetrics and Gynecology, Division of Urogynecology and Pelvic Reconstructive Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Neurourology and Urodynamics
|September 1, 2022
PubMed
Summary
This summary is machine-generated.

Cognitive function in older women after pelvic organ prolapse surgery remained stable. Memory and attention initially declined but improved by the delayed postoperative assessment, showing no significant long-term cognitive dysfunction.

Keywords:
cognitive functionmemorypelvic organ prolapsesurgery

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Area of Science:

  • Geriatric Medicine
  • Neuroscience
  • Surgical Outcomes

Background:

  • Older women face increased risks of cognitive dysfunction after surgery.
  • Pelvic organ prolapse (POP) surgery is common in older women.
  • Understanding the cognitive impact of POP surgery is crucial for patient care.

Purpose of the Study:

  • To compare neurocognitive domain performance before and after POP surgery in older women.
  • To investigate potential short-term and long-term cognitive changes.
  • To test the hypothesis that memory function would not significantly differ post-surgery.

Main Methods:

  • Prospective cohort study of women aged 60+ undergoing POP surgery.
  • Administered a battery of sensitive neurocognitive tests preoperatively and at two postoperative time points (day 1 and 4-6 weeks).
  • Assessed episodic memory, working memory, decision-making, risk-taking, and sustained attention.

Main Results:

  • Episodic memory and sustained attention performance declined on postoperative day 1 compared to baseline.
  • By the delayed postoperative visit (4-6 weeks), episodic memory performance improved beyond baseline levels.
  • No significant differences were observed in working memory, decision-making, or risk-taking at any postoperative assessment.

Conclusions:

  • Cognitive test scores did not show significant worsening between baseline and delayed postoperative assessments.
  • Older women undergoing POP surgery may experience transient cognitive changes that resolve by 4-6 weeks post-surgery.
  • The study supports the hypothesis that memory function is not significantly impaired long-term after POP surgery.