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Commentary on Questionable High Free T4 Concentrations: When Confirming against an Alternative Method Is Not Enough

Andrew R Crawford1

  • 1Department of Medicine, Endocrinology Section, Dartmouth-Hitchcock Medical Center, 1 Medical Center Drive, Lebanon, NH, USA.

Clinical Chemistry
|September 1, 2022
PubMed
Summary

No abstract available in PubMed .

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Unlike direct titration, back-titration, and displacement titration, indirect titration is an EDTA titration method for quantifying anions. In the indirect titration method, anions are precipitated as their insoluble salts with excess metal ions. The filtrate containing the excess metal ions is directly titrated with standard EDTA until the endpoint is achieved. Another approach involves extracting the metal ion and back-titrating with standard EDTA to obtain the endpoint. In this way, the...