Related Experiment Video
Updated: Jun 27, 2026

10:33
Local Field Fluorescence Microscopy: Imaging Cellular Signals in Intact Hearts
Published on: March 8, 2017
8.4K
Schiff Base Aggregation-Induced Emission Luminogens for Sensing Applications: A Review.
Jingfei Wang1, Qingye Meng1, Yongyan Yang1
1College of Chemistry, Jilin University, Changchun 130012, People's Republic of China.
ACS Sensors
|September 1, 2022
Summary
This review explores Schiff base compounds with aggregation-induced emission (AIE) characteristics for advanced fluorescence sensing. These probes offer sensitive, selective detection, overcoming traditional limitations in high-concentration applications.
Area of Science:
- Analytical Chemistry
- Materials Science
- Organic Chemistry
Background:
- Fluorescence sensing provides sensitive, selective, and rapid detection methods.
- Traditional fluorescent molecules suffer from quenching in aggregated states.
- Aggregation-induced emission (AIE) offers a solution to overcome fluorescence quenching.
Purpose of the Study:
- To review recent advancements in Schiff base compounds exhibiting AIE characteristics.
- To highlight their application as effective fluorescence sensors.
Main Methods:
- Literature review of Schiff base compounds with AIE properties.
- Analysis of their performance as fluorescence sensors for various analytes.
Main Results:
- Schiff base compounds with AIE characteristics demonstrate enhanced fluorescence in aggregated states.
- These probes exhibit high sensitivity, selectivity, and rapid response.
- Successful application in qualitative and quantitative detection of target substrates.
Conclusions:
- Schiff base compounds incorporating AIE properties are promising candidates for advanced fluorescence sensing.
- Their facile synthesis, low toxicity, and design flexibility contribute to their utility.
- These AIE-active Schiff bases offer superior performance over traditional fluorescent probes.
Related Concept Videos
Photoluminescence: Fluorescence and Phosphorescence
Photoluminescence is a process where a molecule absorbs light energy and re-emits it in the form of light. This phenomenon occurs when a substance absorbs photons, promoting its electrons to higher energy level excited states, followed by a relaxation process in which the electrons return to their original ground state energy levels and emit light. Photoluminescence is widely observed in various materials, including semiconductors, and organic and inorganic compounds.
A pair of electrons in a...
A pair of electrons in a...
Photoluminescence: Applications
Photoluminescence offers a wide range of applications due to its inherent sensitivity and selectivity. This technique allows for both direct and indirect analyses of the analyte. Direct quantitative analysis is possible when the analyte exhibits a favorable quantum yield for fluorescence or phosphorescence. However, an indirect analysis may be feasible if the analyte is not fluorescent or phosphorescent, or if the quantum yield is unfavorable. Indirect methods include reacting the analyte with...

