Related Experiment Video
Updated: Aug 30, 2025

A Novel High-Throughput Ex Vivo Ovine Skin Wound Model for Testing Emerging Antibiotics
Published on: September 16, 2022
Pyoderma caused by Proteus mirabilis in sheep
Mostafa Abdollahi1, Ashkan Jebelli Javan2, Sara Shokrpoor3
1Faculty of Veterinary Medicine, Department of Internal Medicine, University of Tehran, Tehran, Iran.
Abstract:
Pyoderma is a purulent skin infection usually caused by bacteria and can be divided into primary and secondary categories based on histology. In the present study, an 18-month-old female mixed breed sheep was examined for pyoderma at the injection site of the enterotoxemia vaccine. After routine bacteriology and histopathology procedures, secondary pyoderma caused by Proteus mirabilis was diagnosed. The bacterium analysed using genome sequencing and new strain called AJJ 2021 was diagnosed. This is the first report of pyoderma caused by Proteus mirabilis in sheep.
Insights
A sheep developed a bacterial skin infection, secondary pyoderma, at a vaccine injection site. Researchers identified Proteus mirabilis as the cause, a novel finding in sheep.
Area of Science:
- Veterinary Dermatology
- Microbiology
- Genomics
Background:
- Pyoderma, a bacterial skin infection, is classified as primary or secondary.
- Enterotoxemia vaccination is a common procedure in sheep.
Observation:
- An 18-month-old sheep presented with pyoderma at the enterotoxemia vaccine injection site.
- Bacteriology and histopathology confirmed secondary pyoderma.
Findings:
- Proteus mirabilis was identified as the causative agent of the secondary pyoderma.
- Genome sequencing revealed a new strain, designated AJJ 2021.
- This marks the first documented case of Proteus mirabilis-induced pyoderma in sheep.
Implications:
- Highlights the potential for bacterial infections at vaccine sites in sheep.
- Emphasizes the importance of identifying specific bacterial pathogens for effective treatment.
- Contributes to the understanding of Proteus mirabilis in ovine health and disease.
Related Concept Videos
Acute Pyelonephritis II: Diagnostic Studies and Management
Bacterial Phylum Spirochaetes
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

