Decrease in serum asprosin levels following six weeks of spinning and stationary cycling training in overweight women

Area of Science:

• Endocrinology
• Exercise Physiology
• Metabolic Health

Background:

• Asprosin, a novel adipokine from white adipose tissue, has an incompletely understood physiological role.
• Overweight women are at increased risk for metabolic disorders, necessitating effective interventions.

Purpose of the Study:

• To investigate the impact of spinning and stationary cycling on serum asprosin levels in overweight women.
• To evaluate the effects of these exercise modalities on lipid profiles and body composition.

Main Methods:

• Forty-five overweight women (BMI > 25 kg/m²) were randomized into control, spinning, or stationary cycling groups.
• Participants engaged in three exercise sessions per week for six weeks.
• Serum asprosin, lipid profiles, and body composition were measured using ELISA, enzymatic methods, and standard protocols.

Main Results:

• Both spinning and stationary cycling significantly reduced weight, BMI, triglycerides, and asprosin levels.
• Spinning uniquely decreased total cholesterol and LDL, while increasing HDL, unlike stationary cycling or the control group.
• No significant changes in Waist-to-Hip Ratio (WHR) were observed between exercise groups.

Conclusions:

• Spinning exercise is effective in lowering serum asprosin levels in overweight women.
• This reduction in asprosin, coupled with improvements in lipid profiles, suggests spinning may mitigate risks associated with metabolic diseases.