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Updated: Aug 30, 2025

Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro
Published on: January 31, 2022
Drug-Induced Liver Injury
1Adult Gerontology, Acute Care Nurse Practitioner Program, Louisiana Health Science Center - New Orleans, 1900 Gravier Street, Suite 156, New Orleans, LA 70112, USA.
Abstract:
Drug-induced liver injury (DILI) is a spectrum of liver injuries that can be classified by phenotype and injury patterns. Some injury patterns can be predicted in a number of drugs that are commonly used in practice, but idiosyncratic reactions are unpredictable and are not dose related. There are diagnostic criteria to assist in the classification of DILI phenotype as well as therapeutic interventions to ensure maximal support to the patient affected with DILI to include referral for liver transplantation in some cases.
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