Related Experiment Video
Updated: Aug 30, 2025

Quantification of Protein Interaction Network Dynamics using Multiplexed Co-Immunoprecipitation
Published on: August 21, 2019
Interplay of simplicial awareness contagion and epidemic spreading on time-varying multiplex networks
Huan Wang1, Hai-Feng Zhang1, Pei-Can Zhu2
1The Key Laboratory of Intelligent Computing and Signal Processing of Ministry of Education, School of Mathematical Science, Anhui University, Hefei 230601, China.
Abstract:
There has been growing interest in exploring the dynamical interplay of epidemic spreading and awareness diffusion within the multiplex network framework. Recent studies have demonstrated that pairwise interactions are not enough to characterize social contagion processes, but the complex mechanisms of influence and reinforcement should be considered. Meanwhile, the physical social interaction of individuals is not static but time-varying. Therefore, we propose a novel sUAU-tSIS model to characterize the interplay of simplicial awareness contagion and epidemic spreading on time-varying multiplex networks, in which one layer with 2-simplicial complexes is considered the virtual information layer to address the complex contagion mechanisms in awareness diffusion and the other layer with time-varying and memory effects is treated as the physical contact layer to mimic the temporal interaction pattern among population. The microscopic Markov chain approach based theoretical analysis is developed, and the epidemic threshold is also derived. The experimental results show that our theoretical method is in good agreement with the Monte Carlo simulations. Specifically, we find that the synergistic reinforcement mechanism coming from the group interactions promotes the diffusion of awareness, leading to the suppression of the spreading of epidemics. Furthermore, our results illustrate that the contact capacity of individuals, activity heterogeneity, and memory strength also play important roles in the two dynamics; interestingly, a crossover phenomenon can be observed when investigating the effects of activity heterogeneity and memory strength.
Related Concept Videos
Causality in Epidemiology
Steps in Outbreak Investigation
Infection
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
Viral Recombination
Nonconscious Mimicry
Cyclic Processes And Isolated Systems
In the case of a non-isolated system, the change in the internal energy is zero only if the process is cyclic. A thermodynamic process is considered cyclic if the system undergoes a series of changes and returns to its initial state.
Consider a cyclic process that returns to its initial state, undergoing a four-step process. The heat transfer along each...

