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Updated: Aug 30, 2025

Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy
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Pla2g2a promotes innate Th2-type immunity lymphocytes to increase B1a cells

Susan A Shinton1, Joni Brill-Dashoff1, Kyoko Hayakawa2

  • 1Fox Chase Cancer Center, 333 Cottman Ave., Philadelphia, PA, 19111, USA.

Scientific Reports
|September 1, 2022
PubMed
Summary

The presence of Pla2g2a is crucial for developing innate immunity in newborns, promoting the growth of B1a cells essential for survival. Its absence hinders this process, impacting immune cell development from neonatal to adult stages.

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