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The role of thrombolysis in hemodialysis access occlusion

J J Schilling, A R Eiser, R F Slifkin

    American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
    |August 1, 1987
    PubMed

    Thirty-eight occluded hemodialysis accesses were infused with urokinase on 43 occasions. In 49% of the cases, the access patency was reestablished for a week or longer, although 38% of this subset subsequently rethrombosed. Postthrombolysis angiography detected a stenotic segment in 14 of 22 angiograms (64%). Local bleeding was common, but the thrombolytic therapy was generally well tolerated. Percutaneous thrombolysis in conjunction with angiography and access revision provides a clinically useful means of access preservation.

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