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Related Concept Videos

Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Related Experiment Video

Updated: Aug 30, 2025

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
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Lower lip recurrent keratoacanthoma: A case report.

Xian-Guang Liu1, Xing-Guang Liu1, Cai-Jiao Wang2

  • 1Department of Oral and Maxillofacial Surgery, Shandong University, Jinan 250100, Shandong Province, China.

World Journal of Clinical Cases
|September 2, 2022
PubMed
Summary
This summary is machine-generated.

Recurrent keratoacanthoma (KA), a rare occurrence after surgery, was successfully treated with topical retinoic acid. This adjuvant therapy demonstrated a good prognosis in a 2-year follow-up, highlighting its potential in managing KA recurrence.

Keywords:
Case reportClinical featuresKeratoacanthomaLower lipRecurrenceSquamous cell carcinoma

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Area of Science:

  • Dermatology
  • Oncology

Background:

  • Keratoacanthoma (KA) is a common, self-limiting skin tumor.
  • Recurrence of KA post-surgical excision is uncommon but documented.

Observation:

  • A 76-year-old male presented with recurrent lower lip KA 6 months after initial resection.
  • The recurrent lesion was surgically excised, followed by topical tretinoin cream application.

Findings:

  • Pathological examination confirmed KA in both instances.
  • The patient showed no signs of recurrence at a 2-year postoperative follow-up with normal mucosal healing.

Implications:

  • Topical retinoic acid may serve as an effective adjuvant treatment for recurrent KA.
  • This approach could potentially improve outcomes and reduce recurrence rates in select KA cases.