Orthostatic hypotension due to hypertrophic cardiomyopathy and autonomic failure

A case of orthostatic hypotension due to the combination of hypertrophic obstructive cardiomyopathy and autonomic failure is described. The interacting pathophysiologic features of the two disorders and response to therapy are discussed. The value of dynamic cardiac auscultation and Doppler echocardiography in patients with postural blood pressure changes is demonstrated.