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Updated: Aug 30, 2025

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Analysis of severity in ischemic stroke patients with coronary artery disease in the telestroke network
Nicolas Poupore1, Camron Edrissi1, Mareshah Sowah1
1University of South Carolina School of Medicine-Greenville, Greenville, SC 29605, USA.
Insights
Patients with acute ischemic stroke and coronary artery disease who also have peripheral vascular disease or hypertension face a higher risk of worsening neurological function. Strategic management is crucial for this high-risk group in telestroke networks.
Area of Science:
- Neurology
- Cardiology
- Vascular Medicine
Background:
- Coronary artery disease (CAD) is a significant comorbidity in patients experiencing acute ischemic stroke (AIS).
- Understanding risk factors for stroke severity in this population is critical for targeted interventions.
Purpose of the Study:
- To identify demographic and clinical risk factors associated with the severity of acute ischemic stroke (AIS) in patients with a history of coronary artery disease (CAD).
Main Methods:
- Utilized multivariate logistic regression models to analyze data from AIS patients with CAD within a telestroke network.
- Assessed factors correlating with worsening or improving neurological function.
Main Results:
- Peripheral vascular disease (OR: 3.995) and hypertension (OR: 6.056) were significantly associated with worsening neurological function in AIS patients with CAD.
- Statistical significance was confirmed with p-values of 0.044 and 0.029, respectively.
Conclusions:
- Hypertension and peripheral vascular disease are key risk factors for poor outcomes in AIS patients with CAD treated via telestroke.
- Development of strategic management plans is recommended to enhance care for this vulnerable patient group.
Abstract:
Aim: This study investigated demographic and clinical risk factors associated with severity in acute ischemic stroke (AIS) patients with a history of coronary artery disease (CAD). Materials & methods: Multivariate logistic regression models were used to determine specific factors associated with worsening or improving neurologic functions among AIS patients with CAD treated in the telestroke. Results: AIS patients with CAD, peripheral vascular disease (OR: 3.995; 95% CI: 1.035-15.413; p = 0.044) and hypertension (OR: 6.056; 95% CI: 1.207-30.374; p = 0.029) were associated with worsening neurologic functions. Conclusion: Our findings suggest the need to develop strategic management to improve the care of AIS patients with a history of CAD that present with hypertension and peripheral vascular disease in the telestroke network.
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