Latent class growth analysis identified different trajectories in cognitive development of extremely low birthweight

Anu Haavisto1,2, Liisa Klenberg3, Viena Tommiska4

  • 1Department of Psychology and Logopedics, University of Helsinki, Helsinki, Finland anu.haavisto@helsinki.fi.

BMJ Paediatrics Open
|September 2, 2022
PubMed

Insights

Cognitive trajectories in extremely low birthweight (ELBW) children vary; those with average or below-average scores at age 5 showed declines by age 11. Neonatal complications and lower maternal education are risk factors for lower intelligence in ELBW children.

Area of Science:

  • Neuroscience
  • Developmental Psychology
  • Pediatrics

Background:

  • Extremely low birthweight (ELBW) children exhibit significant individual variation in cognitive development.
  • Longitudinal studies indicate diverse developmental trajectories in this population.
  • Understanding these trajectories is crucial for targeted interventions.

Purpose of the Study:

  • To characterize distinct cognitive developmental trajectories in extremely low birthweight (ELBW) children from preschool to preteen age.
  • To identify factors influencing cognitive development in ELBW children.
  • To provide insights for clinical management of ELBW individuals.

Main Methods:

  • Prospective neurocognitive follow-up study of 115 extremely low birthweight (ELBW) children.
  • Cognitive assessments using standardized intelligence tests at median ages of 5.0 and 11.3 years.
  • Latent class growth analysis to identify developmental trajectories.

Main Results:

  • Three distinct cognitive trajectories were identified in ELBW children.
  • Children with average or below-average intelligence at age 5 experienced significant score decreases by age 11.
  • Above-average intelligence remained stable, while neonatal complications and maternal education predicted lower intelligence at follow-up.

Conclusions:

  • Extremely low birthweight (ELBW) children form a heterogeneous group with identifiable cognitive trajectories.
  • Cognitive deterioration is more likely in ELBW children with initially average or below-average performance.
  • Neonatal complications and lower maternal education are significant risk factors for poorer cognitive outcomes in ELBW children.
Abstract

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