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Author Spotlight: Advancing Awake Nasotracheal Intubation with Flexible Video Rhino-Laryngoscopes
03:58

Author Spotlight: Advancing Awake Nasotracheal Intubation with Flexible Video Rhino-Laryngoscopes

Published on: August 2, 2024

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Predictors of extubation success: a population-based study of neonates below a gestational age of 26 weeks

Mari Oma Ohnstad1,2, Hans Jørgen Stensvold3,4, Are Hugo Pripp5,6

  • 1Department for Postgraduate Studies, Lovisenberg Diaconal University College, Oslo, Norway mari.oma.ohnstad@ldh.no.

BMJ Paediatrics Open
|September 2, 2022
PubMed

Insights

Extremely premature infants had a 55% success rate on their first extubation attempt. Factors like oxygen needs, sex, and general condition at birth can improve extubation success in these vulnerable infants.

Area of Science:

  • Neonatal Medicine
  • Pediatric Critical Care

Background:

  • Extremely premature (EP) infants require mechanical ventilation.
  • Optimizing extubation readiness is crucial for improving outcomes in EP infants.

Purpose of the Study:

  • To investigate the success rate of first extubation attempts in EP infants.
  • To identify factors influencing successful extubation in this population.

Main Methods:

  • A population-based study analyzed data from EP infants born before 26 weeks gestational age in Norway (2013-2018).
  • Successful extubation was defined as no reintubation within 72 hours.

Main Results:

  • Of 316 first extubation attempts, 55% were successful.
  • Predictors of success from conventional ventilation included lower FiO2, higher Apgar score, higher gestational age, female sex, and higher postnatal age.
  • Lower FiO2 was a predictor of success when extubating from high-frequency oscillatory ventilation.

Conclusions:

  • First extubation success rates in EP infants are around 55%.
  • Clinical judgment can be enhanced by considering oxygen requirements, sex, and general condition at birth to improve extubation outcomes.
Abstract

Keywords:
data collectionneonatology

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