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Investigating the Alleviating Effects of Bacillus cereus Administration on Colitis through Gut Microbiota Modulation
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Compounded Medications and Probiotics for Irritable Bowel Syndrome

Katherine Rivera Nárvaez1, Tara Thompson2

  • 1Revelation Pharma Corporation, Kennesaw, Georgia.

International Journal of Pharmaceutical Compounding
|September 2, 2022
PubMed

Insights

Individuals with irritable bowel syndrome and ulcerative colitis show altered gut microflora. Pharmaceutical compounding offers targeted therapies and customized dosages for these conditions, addressing imbalances in gut bacteria.

Area of Science:

  • Gastroenterology
  • Microbiology
  • Pharmaceutical Sciences

Background:

  • Irritable Bowel Syndrome (IBS) and Ulcerative Colitis (UC) are associated with distinct gut microflora profiles compared to healthy individuals.
  • Alterations include decreased beneficial bacteria, increased pathogenic bacteria, and potential small intestinal bacterial overgrowth (SIBO).

Purpose of the Study:

  • To discuss the role of gut microflora in IBS and UC.
  • To highlight the significance of pharmaceutical compounding in managing these gastrointestinal disorders.

Main Methods:

  • Review of existing studies on gut microflora in IBS and UC.
  • Analysis of the therapeutic potential of pharmaceutical compounding for IBS and UC.

Main Results:

  • Significant differences in microflora composition are observed in patients with IBS and UC.
  • Pharmaceutical compounding can provide targeted treatments and specific dosages not readily available commercially.

Conclusions:

  • Gut microflora dysbiosis is a key factor in IBS and UC pathogenesis.
  • Compounded medications represent a valuable therapeutic option for personalized management of IBS and UC.

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