Retrospective record review on timing of COVID-19 vaccination and cardiac surgery

Jacky Y K Ho1, Ivan C H Siu1, Karen H L Ng1

  • 1Division of Cardiothoracic Surgery, Department of Surgery, Prince of Wales Hospital, Shatin, Hong Kong SAR, China.

Journal of Cardiac Surgery
|September 2, 2022
PubMed

Insights

COVID-19 vaccination is safe for cardiac surgery patients, with minimal adverse effects and no deaths. A 3-6 month post-surgery window is recommended for vaccination, guiding future booster programs.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Public Health

Background:

  • The coronavirus disease 2019 (COVID-19) pandemic presents unique challenges for cardiac surgery.
  • Limited evidence exists regarding COVID-19 vaccination safety and timing in patients undergoing cardiac surgery.
  • Understanding vaccination timing and adverse effects is crucial for patient counseling.

Purpose of the Study:

  • To evaluate the safety and outcomes of COVID-19 vaccination in adult patients following major cardiac surgery.
  • To determine the optimal timing for COVID-19 vaccination in this patient population.
  • To assess the incidence of vaccination-related adverse effects and complications.

Main Methods:

  • A single-center, retrospective observational study included adult cardiac surgery patients from January 2021 to December 2021.
  • Data collected included postoperative clinical outcomes, COVID-19 vaccination status (Sinovac or Pfizer), and adverse events.
  • Vaccination timing relative to surgery was analyzed.

Main Results:

  • Out of 426 patients, 52% received at least one COVID-19 vaccine dose.
  • 15% were vaccinated before surgery, and 36% after surgery, with a mean post-operative first dose at 216 days.
  • Only 1.4% of patients experienced vaccination-related complications, and no vaccine-related mortality was observed.

Conclusions:

  • COVID-19 vaccination is safe for patients post-major cardiac surgery, demonstrating a low rate of adverse effects and no associated mortality.
  • A recommended vaccination timeframe of 3-6 months after cardiac surgery provides a reasonable guideline.
  • These findings can inform future COVID-19 vaccination strategies and booster programs for cardiac surgical patients.
Abstract

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