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Updated: Aug 30, 2025

Assessing Neuroprotective Effects of Glycyrrhizae Radix et Rhizoma Extract Using a Transient Middle Cerebral Artery Occlusion Mouse Model
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Targeting GRK2 and GRK5 for treating chronic degenerative diseases: Advances and future perspectives

Ya Zhang1, Jifa Zhang2, Jiaxing Wang3

  • 1Targeted Tracer Research and Development Laboratory, Institute of Respiratory Health, Frontiers Science Center for Disease-related Molecular Network, Joint Research Institution of Altitude Health, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China; College of Life Sciences, Sichuan University, Chengdu, 610064, Sichuan, China; State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China.

European Journal of Medicinal Chemistry
|September 2, 2022
PubMed

Keywords:
Chronic degenerative diseasesDual-target inhibitorsGRK2GRK5Structure-activity relationship

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