Related Experiment Video
Updated: Aug 30, 2025
12:09
Ex Vivo Porcine Experimental Model for Studying and Teaching Lung Mechanics
Published on: April 19, 2024
1.5K
Collaborative Use of Lung Mechanics Simulation for Testing and Iterative Design for Three Emergency Use Ventilation
1From the Department of Anesthesiology, Perioperative and Pain Medicine (R.M.F., D.M.G.), Stanford University School of Medicine, CA; Simulation Center (D.M.G.), VA Palo Alto Health Care System, CA; and Center for Immersive and Simulation-based Learning (D.M.G.), Stanford University School of Medicine, CA.
Summary
This study used a lung simulator to develop open-source ventilators for COVID-19 patients. Simulation facilitated rapid design iteration and collaboration, proving valuable for healthcare innovation.
Area of Science:
- Biomedical Engineering
- Medical Simulation
- Respiratory Care
Background:
- Development of novel ventilation devices is crucial for managing respiratory illnesses.
- The COVID-19 pandemic highlighted the need for rapid innovation in medical equipment.
- Collaboration between engineering and clinical teams is essential for effective device development.
Purpose of the Study:
- To detail the use of a lung simulator in developing open-source ventilation devices.
- To assess the role of simulation in collaborative healthcare innovation.
- To evaluate the effectiveness of simulation in testing prototypes for emergency use authorization.
Main Methods:
- Utilized the IngMar Medical ASL 5000 lung simulator.
- Programmed 29 software lung models simulating various disease severities.
- Conducted over 200 simulations with real-time design team feedback.
Main Results:
- Successfully aided the development of 3 open-source ventilation devices.
- Enabled rapid troubleshooting and design iteration.
- Facilitated learning across multiple simultaneous projects.
Conclusions:
- Simulation is a powerful tool for collaborative innovation in healthcare.
- Lung simulation accelerates the development and testing of critical medical devices.
- This approach is applicable beyond emergency settings, enhancing everyday healthcare solutions.
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