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Neuromuscular exercise in children with Down Syndrome: a systematic review
Eliana-Isabel Rodríguez-Grande1,2, Olga-Cecilia Vargas-Pinilla3, Martha-Rocio Torres-Narvaez3
1Doctoral Program in Clinical Epidemiology, Pontificia Universidad Javeriana, Bogotá, Colombia. eliana.rodriguez@urosario.edu.co.
Scientific Reports
|September 2, 2022
Summary
Neuromuscular exercise improves muscle strength and balance in children with Down syndrome over 8 years old. This systematic review clarifies effective parameters for these interventions, showing significant gains in strength and stability.
Area of Science:
- Neurology
- Physical Therapy
- Pediatrics
Background:
- Therapeutic exercise parameters for Down syndrome are unclear.
- Need for evidence on neuromuscular exercise effects on balance, strength, and flexibility in children and adolescents with Down syndrome.
Purpose of the Study:
- Systematic review of neuromuscular exercise effectiveness for balance, muscle strength, and flexibility.
- Determine effective intervention parameters in Down syndrome population (6-18 years).
Main Methods:
- Systematic search of PubMed, PEDro, EMBASE, SCIELO, Lilacs, Cochrane Library (May-Dec 2021).
- Inclusion of randomized controlled trials (RCTs).
- Analysis of intervention modes (mechanotherapy, vibration, unstable surfaces), frequency, duration, and intensity.
Main Results:
- Neuromuscular exercise increased chest and lower limb muscle strength (mean 8.51 kg and 21.54 kg, respectively).
- Improved balance observed with isokinetic training and core stability exercises.
- Positive effects noted in children over 8 years; no evidence found for children under 8 years.
Conclusions:
- Neuromuscular exercise is effective for improving muscle strength and balance in children with Down syndrome over 8 years old.
- Specific parameters like frequency (3-5 days/week), duration (6-15 min/session), and intensity (60-80% MVC) are associated with positive outcomes.
- Further research is needed for younger children (under 8 years).

