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Severe Agitation as an Unusual Presentation of Multisystem Inflammatory Syndrome in Children
Mohamed A Ghamry1, Korlos Salib2, Shereen Henin3
1Pediatrics, Al Salam Hospital, Ministry of Health, Port Said, EGY.
Insights
Multisystem inflammatory syndrome in children (MIS-C) can present atypically. Early diagnosis and treatment of this rare COVID-19 complication are crucial for preventing severe outcomes in children.
Area of Science:
- Pediatrics
- Infectious Diseases
- Critical Care Medicine
Background:
- Multisystem inflammatory syndrome in children (MIS-C) is a rare but serious post-COVID-19 hyperinflammatory condition.
- It can lead to severe complications, including death, necessitating prompt recognition.
Observation:
- A four-year-old boy presented with unusual symptoms: severe agitation, muscle spasms, and fever.
- Initial presentation did not immediately suggest MIS-C, highlighting diagnostic challenges.
Findings:
- Further evaluation confirmed findings consistent with MIS-C.
- The child received treatment with intravenous immunoglobulin (IVIG) and steroids.
Implications:
- This case underscores the importance of recognizing atypical MIS-C presentations in pediatric patients.
- Prompt diagnosis and management are vital to improve outcomes and prevent long-term complications.
- Awareness among healthcare professionals is key for timely intervention in MIS-C cases.
Abstract:
Multisystem inflammatory syndrome in children (MIS-C) is a rare hyperinflammatory syndrome that mainly affects children after a primary infection with coronavirus disease 2019 (COVID-19), with the possibility of severe and lethal complications. We report a case of a unique presentation of MIS-C in a four-year-old boy who presented with severe agitation, muscle spasms, and two days of fever. Other findings consistent with MIS-C were revealed later, and he was managed with intravenous immunoglobulin (IVIG) and steroids. He showed a dramatic response of improvement and was discharged. This case report aimed to raise health professionals' awareness about the atypical presentations of MIS-C and the importance of early diagnosis, treatment, and follow-up MIS-C cases to avoid complications affecting children's lives.
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