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Updated: Aug 29, 2025
Author Spotlight: Assessing Ischemic Stroke Damage Through Middle Cerebral Artery Occlusion Model
Published on: August 11, 2023
Massive Left Ventricular Thrombus Causing Bilateral Posterior Cerebral Artery Stroke: A Case Report and Review of
Ashali Jain1, Asad Haider1, Tyler S Jones1
1Internal Medicine, University of Central Florida College of Medicine/HCA Florida North Florida Hospital, Gainesville, USA.
Insights
Left ventricular thrombus (LVT) can cause serious embolic strokes. Prompt anticoagulation is crucial for managing LVT and preventing complications like posterior cerebral artery strokes, as demonstrated in this case.
Area of Science:
- Cardiology
- Neurology
- Vascular Medicine
Background:
- Left ventricular thrombus (LVT) is a significant complication following acute myocardial infarction (MI).
- Embolic events from LVT can lead to severe neurological deficits.
- Delayed diagnosis and treatment of LVT can result in poor patient outcomes.
Abstract:
Left ventricular thrombus (LVT) is a major complication of acute myocardial infarction (MI). Here, we describe the case of a 36-year-old female with a history of acute anterior MI six years prior to hospitalization, who presented with bilateral vision loss due to a bilateral embolic posterior cerebral artery (PCA) stroke in the setting of a 5.7 x 1.7 cm LVT. She underwent bilateral PCA thrombectomy, which led to improvement of her symptoms. Her LVT was managed non-surgically with apixaban and clopidogrel. Her case highlights the need for more medical education about LVT, as quick initiation of anticoagulation is essential in improving outcomes. We review the existing literature to explain the pathogenesis, diagnosis, and treatment of LVT.
