Anti-colorectal cancer effects of seaweed-derived bioactive compounds

Yunhua Fu1, Dong Xie1, Yinghao Zhu1

  • 1Changchun University of Chinese Medicine, Changchun, China.

Frontiers in Medicine
|September 5, 2022
PubMed

Insights

Seaweeds contain bioactive compounds with anticancer properties, particularly effective against colorectal cancer. This review highlights their potential to eradicate or slow cancer progression by inducing apoptosis.

Area of Science:

  • Marine Biology
  • Pharmacology
  • Oncology

Background:

  • Seaweeds, including Chlorophyta, Rhodophyta, and Phaeophyta, are rich sources of novel therapeutic compounds.
  • These marine algae exhibit diverse bioactive properties, notably anticancer activities.
  • Colorectal cancer remains a leading cause of cancer-related mortality worldwide.

Purpose of the Study:

  • To review seaweed-derived compounds with demonstrated efficacy against colorectal cancer.
  • To explore the mechanisms by which these compounds induce cancer cell death (apoptosis).
  • To emphasize the therapeutic potential of seaweeds in combating colorectal cancer.

Main Methods:

  • Literature review of scientific studies on seaweed compounds and colorectal cancer.
  • Analysis of research detailing the anticancer mechanisms of seaweed extracts.
  • Examination of *in vitro* and *in vivo* studies on seaweed-derived therapeutics.

Main Results:

  • Various seaweed-derived compounds show significant activity against colorectal cancer cells.
  • These compounds have demonstrated the ability to eradicate or inhibit cancer progression.
  • Mechanisms include the induction of apoptosis in cancer cells, both in laboratory and living systems.

Conclusions:

  • Seaweed compounds represent a promising natural resource for colorectal cancer therapy.
  • Further research into seaweed-derived agents could lead to novel anticancer drugs.
  • The bioactive compounds in seaweeds offer potential for developing effective treatments against colorectal cancer.

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