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Pressure sore carcinoma.

J C Grotting, J Bunkis, L O Vasconez

    Annals of Plastic Surgery
    |June 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

    Squamous cell carcinoma in pressure sores is rare but aggressive. Most patients with this cancer die within 17 months due to recurrence or metastasis, highlighting poor prognosis.

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    Area of Science:

    • Oncology
    • Dermatology
    • Surgical Pathology

    Background:

    • Pressure sores affect elderly and paraplegic populations, carrying a risk of malignant transformation.
    • Squamous cell carcinoma (SCC) developing in chronic wounds is uncommon but clinically significant.

    Purpose of the Study:

    • To review the clinical course and outcomes of patients diagnosed with pressure sore carcinoma.
    • To identify key clinical features and prognostic factors for SCC arising in pressure sores.

    Main Methods:

    • Retrospective review of 10 patient cases with pressure sore carcinoma.
    • Analysis of clinical presentation, treatment (resection and flap closure), and patient outcomes.

    Main Results:

    • The majority of tumors were well-differentiated SCCs.

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  • 80% of patients died from recurrence or metastases within an average of 17 months post-surgery.
  • Two patients had favorable outcomes: one lost to follow-up at 2 years, one disease-free at 3 months.

    • Conclusions:

    • A velvety, cauliflower-like growth on a chronic pressure sore warrants suspicion for malignancy.
    • Pressure sore carcinoma has a high mortality rate, suggesting rapid progression and potential role of altered immunocompetence.
    • Surgical intervention, while necessary, may be associated with rapid tumor progression.