Relationship of anemia with COVID-19 deaths: A retrospective cross-sectional study

Manish Jha1, M L Tak1, Rashmi Gupta1

  • 1Department of Anesthesia, Dr. S. N. Medical College and Associated Hospitals, Jodhpur, Rajasthan, India.

Insights

Anemia significantly correlates with COVID-19 severity and mortality. Hemoglobin levels can serve as a prognostic marker for risk stratification in patients with COVID-19.

Area of Science:

  • Medical Research
  • Clinical Medicine
  • Public Health

Background:

  • The second wave of COVID-19 in India resulted in substantial mortality.
  • Investigating factors influencing COVID-19 severity is crucial for patient management.

Purpose of the Study:

  • To determine the impact of anemia on COVID-19 severity.
  • To evaluate hemoglobin (Hb) as a prognostic marker for disease severity.

Main Methods:

  • Retrospective analysis of 784 patients admitted to a COVID adult intensive care unit (ICU).
  • Anemia classification based on World Health Organization (WHO) guidelines.
  • Statistical analysis using the Chi-squared test to assess the relationship between anemia and mortality.

Main Results:

  • Out of 784 patients, 507 died from COVID-19.
  • Nearly half (49.3%) of deceased patients had anemia.
  • Anemia showed a significant correlation with COVID-19 death in both males and females, and in patients with no other comorbidities.

Conclusions:

  • Anemia is an independent prognostic risk factor for COVID-19 severity.
  • Hemoglobin concentration can be utilized for risk stratification in COVID-19 patients.
  • Anemia management may be important in mitigating COVID-19 outcomes.
Abstract

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