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Updated: Aug 29, 2025

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
Published on: May 31, 2016
Pulmonary calcinosis associated with Alport syndrome
Valentine Mismetti1, Marie-Pierre Perquis1, Lina Hamdi1
1Department of Pulmonology and Thoracic Oncology, North Hospital, University Hospital of Saint-Etienne, France.
Abstract:
We report the case of a 48-year-old woman under dialysis from chronic renal failure (CRF) since the age of 27, due to Alport syndrome. The patient underwent routine chest X-ray on which diffuse micronodules were shown. Chest computed tomography showed partially calcified micronodules with centrilobular distribution respecting the subpleural spaces and predominant in the upper lobar regions. Metastatic pulmonary calcinosis was confirmed by the bone scan with an overall course of 29 years. This is the first reported case of pulmonary calcinosis from CRF due to Alport syndrome.
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