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A Preclinical Model of Orthotopic Heart Transplantation in Bama Miniature Pigs Using Biatrial Technique
Published on: June 13, 2025
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Anatomical Differences Between Human and Pig Hearts and Their Relevance for Cardiac Xenotransplantation Surgical
Aakash Shah1, Corbin E Goerlich1, Chetan Pasrija1
1Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland, USA.
JACC. Case Reports
|September 5, 2022
Abstract:
Cardiac xenotransplantation has been proposed to bridge the gap between supply and demand for patients with end-stage heart failure requiring transplantation. However, differences in pig anatomy compared with human anatomy require modification of the surgical approach. In addition, careful consideration should be given to size matching before transplantation. (Level of Difficulty: Advanced.).

