Association Between COVID-19 Vaccination Coverage and Case Fatality Ratio: a Comparative Study - Hong Kong SAR, China

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Guanhao He1, Sui Zhu2, Di Fu1

  • 1Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou City, Guangdong Province, China.

China CDC Weekly
|September 5, 2022
PubMed

Insights

Low vaccination rates in Hong Kong led to a high Omicron case fatality ratio, unlike Singapore. This highlights the critical need for accessible vaccines, especially for the elderly, to prevent severe outcomes.

Area of Science:

  • Epidemiology
  • Public Health
  • Infectious Diseases

Background:

  • Hong Kong Special Administrative Region (SAR), China, and Singapore experienced significant Omicron variant epidemics.
  • Hong Kong SAR, China, faced an overwhelmed medical system and a high case fatality ratio (CFR), while Singapore did not.

Purpose of the Study:

  • To investigate the reasons behind the differing outcomes of the Omicron epidemic in Hong Kong SAR, China, and Singapore.
  • To emphasize the importance of vaccination in mitigating severe outcomes during an epidemic.

Main Methods:

  • Comparative analysis of epidemic data between Hong Kong SAR, China, and Singapore.
  • Correlation analysis between vaccination coverage and case fatality ratios.

Main Results:

  • Low vaccination coverage, particularly among older adults in Hong Kong SAR, China, was identified as a primary driver of its high CFR.
  • Singapore's higher vaccination rates likely contributed to its lower CFR.

Conclusions:

  • Vaccination is crucial for reducing mortality during Omicron variant epidemics.
  • Public health strategies should prioritize increasing vaccination coverage, especially in vulnerable populations like the elderly, to prevent severe outcomes and healthcare system strain.
Abstract

Keywords:
COVID-19case fatality ratethe elderlyvaccine

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