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Sleep pattern in relation to recurrent osteoporotic fracture in the elderly
Likang Li1, Haobin Zeng2, Bo Zhang2
1Center for Clinical Epidemiology and Methodology (CCEM), Guangdong Second Provincial General Hospital, Guangzhou, China.
A higher overall sleep score significantly increases the risk of recurrent osteoporotic fractures in elderly patients. Poor sleep patterns were not significantly linked to increased fracture risk in this study.
Area of Science:
- Gerontology
- Sleep Medicine
- Orthopedics
Background:
- Previous research focused on individual sleep behaviors and fracture risk.
- This study examines the combined effect of multiple sleep behaviors on recurrent fracture risk.
Purpose of the Study:
- To investigate the association between a comprehensive sleep pattern and the risk of imminent recurrent osteoporotic fractures in elderly patients hospitalized with an initial fracture.
Main Methods:
- Prospective cohort study including patients aged 55+ hospitalized for an osteoporotic fracture.
- Sleep patterns were categorized into healthy, intermediate, and poor based on an overall sleep score.
- Cox proportional hazard models were used to analyze the relationship between sleep patterns and recurrent fractures.
Main Results:
- A total of 185 elderly patients (mean age 71.5 years, 87% female) were analyzed with a mean follow-up of 14.7 months.
- Ten (5.4%) recurrent osteoporotic fractures occurred.
- A higher overall sleep score was significantly associated with recurrent fractures (p=0.038).
- Each one-point increase in the overall sleep score correlated with a 60% increased fracture risk (HR=1.60).
Conclusions:
- Increased overall sleep score is a significant risk factor for recurrent osteoporotic fractures in the elderly.
- Intermediate and poor sleep patterns showed non-significant trends towards increased fracture risk.
- Further high-quality research is needed to confirm the relationship between sleep patterns and recurrent osteoporotic fractures in older adults.
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