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Updated: Aug 29, 2025

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Ventricular arrhythmias are associated with increased QT interval and QRS dispersion in patients with ST-elevation

Elibet Chávez-González1, Ailed Elena Rodríguez-Jiménez2, Carlos Javier Ferrer-Rodríguez2

  • 1Electrophysiology Department, Cardiocentro Ernesto Che Guevara, Santa Clara, Cuba.

Revista Portuguesa De Cardiologia : Orgao Oficial Da Sociedade Portuguesa De Cardiologia = Portuguese Journal of Cardiology : an Official Journal of the Portuguese Society of Cardiology
|September 5, 2022
PubMed

Insights

Electrocardiogram findings like QT interval duration and QRS dispersion can predict ventricular arrhythmias (VA) after ST-segment elevation myocardial infarction (STEMI). These ECG markers help stratify risk in heart attack patients.

Area of Science:

  • Cardiology
  • Clinical Electrophysiology

Background:

  • Electrocardiography (ECG) is crucial for diagnosing ST-segment elevation myocardial infarction (STEMI) and assessing arrhythmia risk.
  • Predicting ventricular arrhythmias (VA) post-STEMI is vital for patient management and outcomes.

Purpose of the Study:

  • To identify specific electrocardiographic variables that predict the occurrence of VA in STEMI patients.
  • To differentiate predictors of early-onset versus late-onset VA.

Main Methods:

  • An observational study of 667 STEMI patients was conducted.
  • ECG variables analyzed included QT interval and dispersion, QRS duration and dispersion, and ST-segment elevation.
  • Statistical regression models and regression trees were employed to identify predictive factors.

Main Results:

  • Ventricular arrhythmias (VA) occurred in 13.8% of patients.
  • Predictive ECG variables for VA included prolonged QT interval (>529 ms), increased QT dispersion (>66 ms), and increased QRS dispersion (>50 ms).
  • ST-segment elevation in six or more leads was also associated with VA.

Conclusions:

  • QT interval duration was the primary predictor of VA within the initial 48 hours post-STEMI.
  • QRS dispersion emerged as the main predictor of VA occurring after the initial 48-hour period.
Abstract

Keywords:
Avaliação do riscoDispersão do QRSEnfarte do miocárdioIntervalo QTMyocardial infarctionQRS dispersionQT intervalRisk assessment

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