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New imidazole-5-carbohydroxamic acids with biological activity
Arzneimittel-Forschung
|April 1, 1987
Abstract:
A series of 1-benzyl-2-arylthio (or heteroarylthio)-5-imidazolecarbohydroxamic acids (Va-e) was prepared starting from the corresponding imidazole-5-carboxylic acids IIIa-e via acid chlorides IVa-e. Tests of biological activity showed that compounds Va-e are fairly active against Escherichia coli and Candida albicans.