Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics01:23

Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics

398
Respiratory symptoms, such as congestion and cough, commonly accompany respiratory tract conditions. Various medications, such as antitussives, expectorants, and mucolytics, play crucial roles in providing relief.
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla.  Benzonatate operates peripherally within the respiratory tract by...
398
Types of Toxins01:36

Types of Toxins

1.9K
Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
1.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multi-source apportionment and speciation drivers of heavy metals in the desert-oasis ecotone.

Journal of environmental sciences (China)·2026
Same author

Foundation model for screening severe mitral regurgitation and severe aortic stenosis from coronary angiograms.

Visual computing for industry, biomedicine, and art·2026
Same author

Trends in mortality and leading causes of death among US women during the menopausal transition, 1999-2023.

The American journal of the medical sciences·2026
Same author

Temporal trends in risk of acute kidney injury among patients with preeclampsia in Canada: a retrospective cohort study.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne·2026
Same author

Distribution of Aquatic Vertebrates in the Winter Dry Season Informing Water Resource Management in a Large Floodplain Lake.

Biology·2026
Same author

Lignes directrices de pratique clinique n° 468 : Prise en charge clinique de l'endométriose.

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC·2026

Related Experiment Video

Updated: Aug 29, 2025

Long-term Behavioral and Reproductive Consequences of Embryonic Exposure to Low-dose Toxicants
07:08

Long-term Behavioral and Reproductive Consequences of Embryonic Exposure to Low-dose Toxicants

Published on: March 6, 2018

6.2K

Prenatal pyrethroid exposure and lung function among school-aged children.

Peipei Hu1, Yan Zhang2, Angela Vinturache3

  • 1Department of Respiratory Medicine, Shanghai Children's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

International Journal of Hygiene and Environmental Health
|September 6, 2022
PubMed
Summary
This summary is machine-generated.

Prenatal exposure to pyrethroid insecticides (PYRs) may affect children's lung function. Higher 3-phenoxybenzoic acid (3-PBA) levels were linked to reduced FEV1/FVC, especially in girls.

Keywords:
ChildrenChinaLung functionPrenatalPyrethroid insecticide

More Related Videos

Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes
05:13

Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes

Published on: February 28, 2025

323
Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

86.3K

Related Experiment Videos

Last Updated: Aug 29, 2025

Long-term Behavioral and Reproductive Consequences of Embryonic Exposure to Low-dose Toxicants
07:08

Long-term Behavioral and Reproductive Consequences of Embryonic Exposure to Low-dose Toxicants

Published on: March 6, 2018

6.2K
Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes
05:13

Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes

Published on: February 28, 2025

323
Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

86.3K

Area of Science:

  • Environmental Health
  • Pediatric Pulmonology
  • Toxicology

Background:

  • Limited evidence exists on prenatal pyrethroid insecticide (PYR) exposure effects on childhood lung function.
  • Previous studies primarily focused on respiratory symptoms, not lung function parameters.

Purpose of the Study:

  • To investigate the association between prenatal PYR exposure and lung function in Chinese children.
  • To assess if PYR metabolites impact spirometry measures in early childhood.

Main Methods:

  • Included 233 mother-child dyads from the Laizhou Wan Birth Cohort (LWBC).
  • Measured three PYR metabolites (3-PBA, cis-DCCA, trans-DCCA) in maternal urine via GC-MS.
  • Assessed child lung function using spirometry in children aged 6-8 years; analyzed associations using regression models.

Main Results:

  • 3-phenoxybenzoic acid (3-PBA) was the most frequently detected PYR metabolite.
  • Higher prenatal 3-PBA concentrations were associated with a 1% decrease in FEV1/FVC.
  • A suggestive dose-response trend (p=0.085) and increased susceptibility in girls (p=0.011) were observed; trans-DCCA showed no association.

Conclusions:

  • Prenatal exposure to 3-PBA is associated with a modest reduction in FEV1/FVC in school-aged children.
  • The negative impact on lung function appears more pronounced in girls.
  • Further research is needed to confirm these findings and explore underlying mechanisms.