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At-home ketamine; still a lot to learn

Samuel T Wilkinson1, Gerard Sanacora1

  • 1Department of Psychiatry, School of Medicine, Yale University, New Haven, CT, USA.

Journal of Affective Disorders
|September 6, 2022
PubMed
Abstract

No abstract available in PubMed .

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Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
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