Pharmacogenomics in Targeted Therapy and Supportive Care Therapies for Cancer

Area of Science:

• Oncology
• Pharmacogenomics
• Genetics

Background:

• Targeted therapies and supportive care have advanced cancer treatment.
• However, individual patient responses vary significantly in efficacy and toxicity.
• Pharmacogenomics offers a way to predict these individual responses.

Purpose of the Study:

• To review the current knowledge and clinical applications of pharmacogenomics in targeted cancer therapy.
• To explore hypotheses and emerging practices in this field.
• To briefly discuss pharmacogenomics in cancer supportive care.

Main Methods:

• Literature review of current knowledge, hypotheses, and clinical practices.
• Focused review on pharmacogenomics in targeted cancer therapy.
• Inclusion of pharmacogenomics in supportive cancer therapies.

Main Results:

• Pharmacogenomics holds significant potential for tailoring cancer therapies.
• Identifies patients at high risk for toxicity or likely to benefit from specific treatments.
• The field is rapidly evolving with ongoing research and clinical integration.

Conclusions:

• Pharmacogenomics is crucial for optimizing targeted and supportive cancer care.
• Personalized medicine approaches using pharmacogenomics can improve patient outcomes.
• Further research is needed to fully integrate pharmacogenomics into routine cancer treatment.