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Recent Advanced in MXene Research toward Biosensor Development.

Md Romzan Ali1,2, Md Sadek Bacchu1,2, Md Rashid Al-Mamun1,2

  • 1Department of Chemical Engineering, Jashore University of Science and Technology, Jashore, Bangladesh.

Critical Reviews in Analytical Chemistry
|September 7, 2022
PubMed
Summary

MXene, a novel 2D nanomaterial, offers unique properties for advanced applications. This review details MXene synthesis, functionalization, and its use in biosensors for detecting various targets.

Keywords:
2D nanomaterialsMXenebiomoleculesbiosensorcancer biomarkerhazardous pollutantmycotoxinnext-generation diagnostic toolpathogenic bacteria and virus

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Area of Science:

  • Materials Science
  • Nanotechnology
  • Chemistry

Background:

  • MXene represents a significant advancement in 2D materials, analogous to graphene's discovery.
  • These materials, including transition metal carbonitrides, nitrides, and carbides, are synthesized from MAX phases.
  • MXenes possess advantageous properties like high conductivity, large surface area, and biocompatibility.

Purpose of the Study:

  • To review the structure, synthesis, and functionalization of MXene materials.
  • To explore MXene-based platforms for diverse sensing applications.
  • To highlight MXene's potential in next-generation diagnostic tools.

Main Methods:

  • Synthesis via etching or exfoliation of MAX phases.
  • Surface functionalization through covalent and non-covalent modifications.
  • Review of MXene-based detection platforms and their applications.

Main Results:

  • MXenes exhibit tunable properties through surface functionalization.
  • Demonstrated applications in catalysis, energy storage, sensing, and biomedicine.
  • Successful use in detecting biomolecules, pathogens, cancer biomarkers, and pollutants.

Conclusions:

  • MXene's versatile properties make it ideal for advanced sensing applications.
  • MXene-based biosensors show promise as next-generation diagnostic tools.
  • Further research is crucial to fully realize MXene's potential in innovative detection mechanisms.