Related Experiment Video
Updated: Aug 29, 2025

A Novel Bayesian Change-point Algorithm for Genome-wide Analysis of Diverse ChIPseq Data Types
Published on: December 10, 2012
Compromised item detection: A Bayesian change-point perspective
Yang Du1, Susu Zhang2, Hua-Hua Chang3
1Department of Educational Psychology, University of Illinois, Urbana-Champaign, Urbana-Champaign, Illinois, USA.
Abstract:
Psychometric methods for accurate and timely detection of item compromise have been a long-standing topic. While Bayesian methods can incorporate prior knowledge or expert inputs as additional information for item compromise detection, they have not been employed in item compromise detection itself. The current study proposes a two-phase Bayesian change-point framework for both stationary and real-time detection of changes in each item's compromise status. In Phase I, a stationary Bayesian change-point model for compromise detection is fitted to the observed responses over a specified time-frame. The model produces parameter estimates for the change-point of each item from uncompromised to compromised, as well as structural parameters accounting for the post-change response distribution. Using the post-change model identified in Phase I, the Shiryaev procedure for sequential testing is employed in Phase II for real-time monitoring of item compromise. The proposed methods are evaluated in terms of parameter recovery, detection accuracy, and detection efficiency under various simulation conditions and in a real data example. The proposed method also showed superior detection accuracy and efficiency compared to the cumulative sum procedure.
Related Concept Videos
Difference from Background: Limit of Detection
The LOD indicates the presence or absence...
Detection of Gross Error: The Q Test
Quantifying and Rejecting Outliers: The Grubbs Test
Point and Frameshift Mutations
Outliers and Influential Points
Critical Region, Critical Values and Significance Level
In hypothesis testing, a sample statistic is converted to a test statistic using z, t, or chi-square distribution. A critical region is an area under the curve in probability distributions demarcated by the critical value. When the test statistic falls in this region, it suggests that the null hypothesis must be rejected. As this region contains all those values of the...

