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Updated: Aug 29, 2025

Intravital Microscopy of the Inguinal Lymph Node

Intravital Microscopy of the Inguinal Lymph Node

Published on: April 4, 2011

Diffuse large B-cell lymphoma presenting as an inguinal hernia - case report.

Sam Kinet¹, Eddy F P Kuppens², Hendrik Maes²

¹KU Leuven, AZ Alma (General Hospital), Eeklo, Belgium.

Acta Chirurgica Belgica

|September 7, 2022

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A rare case of diffuse large B-cell lymphoma (DLBCL) presented as an inguinal hernia. Diagnosis required surgical exploration, revealing a paratesticular tumor treated successfully with chemotherapy.

Area of Science:

Oncology
Surgical Pathology
Genitourinary Oncology

Background:

Diffuse large B-cell lymphoma (DLBCL) rarely mimics inguinal hernias.
A 73-year-old male with a history of bilateral inguinal hernia repair presented with a recurrent groin bulge.

Observation:

Sonography suggested recurrent inguinal hernia, but intraoperative findings revealed a lump attached to the spermatic cord without a hernial sac.
A possible malignant etiology was suspected, leading to orchiectomy and lump resection.

Findings:

Histopathology confirmed DLBCL with a non-germinal center phenotype and c-MYC rearrangement.
Staging revealed stage IE disease with extranodal paratesticular involvement.

Implications:

Keywords:

DLBCL case report hernia inguinal misdiagnosis

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Last Updated: Aug 29, 2025

Intravital Microscopy of the Inguinal Lymph Node

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Spinal Hernia Repair and Cauda Equina Repositioning After Lumbar Decompression under Three-Dimensional Microscopy: A Case Report and Literature Review

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This case highlights the importance of considering rare differentials for inguinal swelling.

Early diagnosis and appropriate treatment, such as rituximab-based chemotherapy, can lead to complete remission in paratesticular DLBCL.