Related Experiment Video
Updated: Aug 29, 2025

Objective Nociceptive Assessment in Ventilated ICU Patients: A Feasibility Study Using Pupillometry and the Nociceptive Flexion Reflex
Published on: July 4, 2018
Consensus statement on smoking cessation in patients with pain.
Hiroki Iida1,2,3, Shigeki Yamaguchi4,5, Toru Goyagi4,6
1Working Group on the Role of Smoking Cessation in Pain Relief, The Japan Society of Pain Clinicians (JSPC), Tokyo, Japan. h-iidamd@xqd.biglobe.ne.jp.
Smoking impacts pain sensitivity, causing tolerance and increased sensitivity with long-term use. Smoking cessation is vital for pain management and reducing tobacco-related health risks.
Area of Science:
- Pain Management
- Addiction Medicine
- Tobacco Control
Background:
- Smoking is linked to numerous cancers and cardiovascular/respiratory diseases.
- Limited data exist on smoking's effects on acute and chronic pain.
- Nicotine in tobacco smoke plays a key role in pain pathophysiology.
Purpose of the Study:
- To summarize evidence on smoking's impact on pain.
- To highlight the importance of smoking cessation for patients experiencing pain.
- To inform healthcare professionals about smoking cessation benefits in pain management.
Main Methods:
- Literature review of studies on smoking and pain.
- Analysis of nicotine's role in pain perception and neuronal changes.
- Synthesis of data on smoking cessation outcomes in pain patients.
Main Results:
- Nicotine initially offers acute pain relief but leads to tolerance and heightened pain sensitivity with chronic use.
- Nicotinic acetylcholine receptor desensitization and neuronal plasticity contribute to increased pain sensitivity.
- Smoking cessation can improve pain outcomes and reduce risks of tobacco-related disorders.
Conclusions:
- Smoking cessation interventions are crucial for patients with pain.
- Quitting smoking can alleviate pain, improve daily functioning, and enhance treatment outcomes for underlying conditions.
- Healthcare providers should prioritize smoking cessation discussions with pain patients.
More Related Videos
Related Concept Videos
Analgesia and Pain Management
Chronic Obstructive Pulmonary Disease-V: Management
Smoking Cessation
Acute Coronary Syndrome IV: Interprofessional Care
Peripheral Artery Disease III: Interprofessional Care
Chronic Obstructive Pulmonary Disease-V: Nursing Management
Assessment
Chronic Obstructive Pulmonary Disease
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...

