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Published on: May 7, 2015
Hemophilia B acquired after cadaveric liver transplantation: a case report
Larissa Machado E Silva Gomide1, Viktoria Weihermann2, Isabella Corrêa de Oliveira2
1Department of Gastrointestinal Surgery and Liver Transplantation, Clinical Hospital of the Federal University of Paraná, Curitiba, PR, Brasil.
Abstract:
Hemophilia B is a recessive hereditary disease, and manifestations result from coagulation factor IX deficiency. Although improbable, as factor IX is produced exclusively in the liver, the possibility of developing the disease after transplantation represents an infrequent but potentially morbid complication. Standard laboratory tests may be insufficient to determine the probability of transmission of this pathology. This report describes the case of a patient who developed hemophilia B after liver transplantation whose donor had no prior knowledge of the disease.
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