Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Depression: Overview01:18

Depression: Overview

326
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
326
Depressive Disorders: MDD and Dysthymia01:27

Depressive Disorders: MDD and Dysthymia

202
Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
202
Treatment Strategies for Psychological Disorders01:24

Treatment Strategies for Psychological Disorders

256
Treatment approaches for psychological disorders fall into three main categories: psychological, biological, and sociocultural. Each approach targets different aspects of mental health, requiring varying levels of education and training.
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...
256
Antidepressant Drugs: Overview01:25

Antidepressant Drugs: Overview

708
Antidepressant drugs are a class of medications primarily used for treating various mood disorders, including major depression, anxiety disorders, and other related conditions. These medicines work by modulating the neurotransmitter balance within the brain, alleviating depressive symptoms. Antidepressants can be broadly categorized into several groups according to their mechanism of action and chemical structure: Selective Serotonin Reuptake Inhibitors (SSRIs), Serotonin-Norepinephrine...
708
Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

157
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
157
Antidepressant Drugs: MAOIs and Other Agents01:23

Antidepressant Drugs: MAOIs and Other Agents

315
Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
315

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Static Electricity-Induced Luminescence Materials for Charge Sensing.

Materials (Basel, Switzerland)·2026
Same author

Effects of audio guided loving kindness meditation on psychological well being and laboratory stress responsiveness in healthy university students.

Scientific reports·2026
Same author

Risk factors for free flap failure in the reconstruction of diabetic foot ulcers.

Journal of plastic surgery and hand surgery·2025
Same author

Visceral Fat and Ossification of the Posterior Longitudinal Ligament: Insights From a Japanese Cohort.

JB & JS open access·2025
Same author

The Relationship of Meniscal Extrusion to Subchondral Bone Density in Medial Knee Osteoarthritis.

Orthopaedic journal of sports medicine·2025
Same author

Meniscus extrusion and lower leg alignment predict the distribution of subchondral bone density across the knee joint.

The Knee·2025

Related Experiment Video

Updated: Aug 29, 2025

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
07:30

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Published on: August 18, 2020

6.8K

Interventions for Co-occurring Cannabis Use and Depression.

Tomoya Sato1,2

  • 1Department of Plastic and Reconstructive Surgery, Saitama Medical University, Saitama, JPN.

Cureus
|September 8, 2022
PubMed
Summary

This review found that while pharmacological treatments for depression in cannabis users were ineffective, psychological interventions like cognitive behavior therapy (CBT) and motivational interviewing (MI) show promise for improving symptoms and reducing cannabis dependence.

Keywords:
cannabis usedepressionmotivational interviewingrandomized controlled studysubstance abuse

More Related Videos

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
04:29

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression

Published on: January 7, 2019

28.8K
Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
04:33

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Published on: April 26, 2024

768

Related Experiment Videos

Last Updated: Aug 29, 2025

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
07:30

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Published on: August 18, 2020

6.8K
Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
04:29

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression

Published on: January 7, 2019

28.8K
Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
04:33

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Published on: April 26, 2024

768

Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Addiction Medicine

Background:

  • Comorbid depression and cannabis use represent a significant clinical challenge.
  • Effective interventions for this dual diagnosis are urgently needed.

Purpose of the Study:

  • To review and synthesize evidence on interventions for depression in patients with a history of cannabis use.
  • To evaluate the efficacy of pharmacological and psychological treatments.

Main Methods:

  • Systematic review of English-language, peer-reviewed human studies.
  • Inclusion of randomized controlled trials, non-randomized trials, and single-group trials.
  • Analysis of eight studies evaluating pharmacological and psychological interventions.

Main Results:

  • Pharmacological interventions (quetiapine, venlafaxine, fluoxetine) showed no effectiveness in improving depression.
  • Cognitive behavior therapy (CBT) demonstrated potential in improving depression and cannabis dependence.
  • Motivational interviewing (MI) was associated with improvements in cannabis dependence.

Conclusions:

  • CBT and MI may be effective for comorbid depression and cannabis use.
  • Current evidence is limited by the small number and low quality of studies.
  • Higher-quality research is required to confirm the efficacy of these psychological interventions.