Basic kinetics of binding and incorporation with supramolecular aggregates
Related Experiment Video
Updated: Aug 11, 2026

Measuring Biomolecular DSC Profiles with Thermolabile Ligands to Rapidly Characterize Folding and Binding Interactions
Published on: November 21, 2017
Abstract:
Supramolecular particles of spherical shape (such as micelles, vesicles, etc.) are imagined to interact with small (bio)molecules so that either binding or incorporation occurs. This is generally described as an association process whose rate is determined by appropriate diffusion and actual transformation steps. Along these lines pertinent expressions for the phenomenological rate constants are given. In addition, an upper bound for the rate of incorporation has been derived. The results are discussed with respect to their usefulness in practice.
More Related Videos
10:17Creating Highly Specific Chemically Induced Protein Dimerization Systems by Stepwise Phage Selection of a Combinatorial Single-Domain Antibody Library
Published on: January 14, 2020
06:48Single-Molecule Measurement of Protein Interaction Dynamics Within Biomolecular Condensates
Published on: January 5, 2024
Related Concept Videos
Noncovalent Attractions in Biomolecules
Four types of noncovalent interactions are hydrogen bonds, van der Waals forces, ionic bonds, and hydrophobic interactions.
Hydrogen bonding results from the electrostatic attraction of a hydrogen atom covalently bonded to a strong-electronegative atom like oxygen,...
The Equilibrium Binding Constant and Binding Strength
Ligand Binding and Linkage
The Equilibrium Binding Constant and Binding Strength
Noncovalent Attractions in Biomolecules
Four types of noncovalent interactions are hydrogen bonds, van der Waals forces, ionic bonds, and hydrophobic interactions.
Hydrogen bonding results from the electrostatic attraction of a hydrogen atom covalently bonded to a strong-electronegative atom like oxygen,...
Complexation Equilibria: Overview
The equilibrium constant of the complexation reaction is represented as the formation constant...