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Cycloheximide Chase Analysis of Protein Degradation in Saccharomyces cerevisiae
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SERDs: a case study in targeted protein degradation

Lucia Wang1, Abhishek Sharma1

  • 1Department of Chemistry and Chemical Biology Stevens Institute of Technology Hoboken, New Jersey 07030, USA. abhishek.sharma@stevens.edu.

Chemical Society Reviews
|September 8, 2022
PubMed
Summary

New oral Selective Estrogen Receptor Degraders (SERDs) offer improved options for metastatic breast cancer patients who develop endocrine resistance. This review covers advancements in SERDs and targeted protein degradation therapies.

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