Within-Visit Blood Pressure Variability and Cardiovascular Risk in ELSA-Brasil Study Participants

André Sant'Anna Zarife1,2, Helena Fraga-Maia3, José Geraldo Mill4

  • 1Universidade Federal da Bahia - UFBA, Salvador , BA - Brasil.

Insights

Increased blood pressure variability (BPV) is linked to higher cardiovascular risk in both men and women. This risk is particularly pronounced in men, highlighting BPV as a key indicator for cardiovascular events.

Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Background:

  • Blood pressure variability (BPV) is a recognized prognostic indicator for cardiovascular outcomes.
  • Understanding BPV's role in cardiovascular risk is crucial for preventative strategies.

Purpose of the Study:

  • To investigate the association between within-visit blood pressure variability (BPV) and cardiovascular risk.
  • To analyze this association in participants of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).

Main Methods:

  • A cross-sectional study using baseline data from 14,357 ELSA-Brasil participants without prior cardiovascular disease.
  • Within-visit BPV quantified by coefficient of variation of three standardized systolic blood pressure measurements.
  • Cardiovascular risk assessed using the atherosclerotic cardiovascular disease (ASCVD) risk estimator and logistic regression.

Main Results:

  • Higher cardiovascular risk was significantly associated with increased BPV in both sexes.
  • Men exhibited a higher prevalence of high cardiovascular risk across all BPV quartiles compared to women.
  • Significant associations between higher BPV quartiles and increased cardiovascular risk were observed in both men and women, with a stronger effect in men.

Conclusions:

  • Within-visit blood pressure variability is associated with elevated cardiovascular risk.
  • The association between BPV and cardiovascular risk is particularly significant in men.
Abstract

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