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Updated: Aug 29, 2025

Longitudinal Micro-Computed Tomography Image Analysis for User-Defined Region of Interest in Critical-Sized Bone Defects
Published on: June 24, 2025
Optimization of reconstruction time of ultrasound computed tomography with a piecewise homogeneous region-based
Yu Yuan1, Yue Zhao1, Yang Xiao1
1Control Theory and Engineering, School of Astronautics, Harbin Institute of Technology, PR China.
Abstract:
In this article, a novel ultrasound computed tomography (USCT) reconstruction algorithm for breast imaging is proposed. This algorithm is based on an ultrasound propagation model, the refract-ray model (RRM). In this model, the field of imaging is assumed as piecewise homogenous and is divided into several regions. The ultrasound propagation paths are considered polylines that only refract at the borders of the regions. The edge information is provided by B-mode imaging. Both simulations and experiments are implemented to validate the proposed algorithm. Compared with the traditional bent-ray model (BRM), the time of reconstructions using RRM decreases by over 90 %. In simulations, the imaging qualities for RRM and BRM are comparable, in terms of the root mean square error, the Tenengrad value, and the deformation of digital phantom. In the experiments, a cylindrical agar phantom is imaged using a customized imaging system. When imaging using RRM, the estimate of the phantom radius is about 0.1 mm in error, while it is about 0.3 mm in error using BRM. Moreover, the Tenengrad value of the result using RRM is much higher than that using BRM (9.76 compared to 0.79). The results show that the proposed algorithm can better delineate the phantom within a water bath. In future work, further experimental work is required to validate the method for improving imaging quality under breast-mimicking imaging conditions.
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